Ferret APRIL Recombinant Protein

The Ferret APRIL yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Ferret APRIL applications are for cell culture, ELISA standard, and Western Blot Control. Ferret APRIL yeast-derived recombinant protein can be purchased in multiple sizes. Ferret APRIL Specifications: (Molecular Weight: 16.6 kDa) (Amino Acid Sequence: AALMHKHKQK KKHSVLHLVP INITSKEDSD VTEVMWQPAL KRGRGLEAQG YVVRVWDAGV YLLYSQVLFH DVTFTMGQVV SREGQGRQET LFRCVRSMPS NPDWAYNSCY SAGVFHLHQG DALSVTIPRG RAKLSLSPHG TFLGLVKL (148) ) (Gene ID: 101683970 (Ferret), 116578386 (Ermine) ) . For research use only.

Product Specifications

Background

Tumor necrosis factor ligand superfamily member 13 also known as a proliferation-inducing ligand (APRIL) is a member of the tumor necrosis factor ligand (TNF) ligand family. Nineteen cytokines have been identified as part of the TNF family on the basis of sequence, functional, and structural similarities. Family members include TNF beta (TNFSF1), TNF alpha, Lymphotoxin beta (TNFSF3), OX40 Ligand (TNFSF4), CD40 Ligand (TNFSF5), Fas Ligand (TNFSF6), CD27 Ligand (TNFSF7), CD30 Ligand (TNFSF8), 4-1BB Ligand (TNFSF9), TRAIL (TNFSF10), TRANCE/RANKL (TNFSF11), TWEAK (TNFSF12), APRIL (TNFSF13), BAFF, LIGHT (TNFSF14), TL1A/VEGI (TNFSF15), and GITR Ligand (TNFSF18) . APRIL/TNFSF13 is expressed by macrophages and dendritic cells. APRIL has been shown to play a role in protecting cells from undergoing apoptosis and promoting B cell development.