Feline IL-12/IL-23 p40 Recombinant Protein

The Feline IL-12/IL-23 p40 yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Feline IL-12/IL-23 p40 applications are for cell culture, ELISA standard, and Western Blot Control. Feline IL-12/IL-23 p40 yeast-derived recombinant protein can be purchased in multiple sizes. Feline IL-12/IL-23 p40 Specifications: (Molecular Weight: 35.0 kDa) (Amino Acid Sequence: IWELEKNVYV VELDWHPDAP GEMVVLTCNT PEEDDITWTS DQSSEVLGSG KTLTIQVKEF ADAGQYTCHK GGEVLSHSFL LIHKKEDGIW STDILREQKE SKNKIFLKCE AKNYSGRFTC WWLTAISTDL KFTVKSSRGS SDPQEVTCGA ATLSAEKVRV DNRDYKKYTV ECQEGSACPA AEESLPIEVV VDAIHKLKYE NYTSSFFIRD IIKPDPPKNL QLKPLKNSRH VEVSWEYPDT WSTPHSYFSL TFGVQVQGKN NREKKDRLSV DKTSAKVVCH KDAKIRVQAR DRYYSSSWSN WASVSCS (307) ) (Gene ID: 768273) . For research use only.

Product Specifications

Background

IL-12 is a member of the IL-12 family, which includes IL-12, IL-23, IL-27, and IL-35. Like other IL-12 family members, IL-12 is a heterodimeric cytokine. IL-12 is encoded by two separate genes, IL-12A (p35) and IL-12B (p40) . The active heterodimer, and a homodimer of p40 are formed following protein synthesis. IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of IFN-γ and TNF-α from T and natural killer (NK) cells, and reduces IL-4 mediated suppression of IFN-γ.