Cynomolgus Monkey IL-16 Recombinant Protein

The Cynomolgus Monkey IL-16 yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Cynomolgus Monkey IL-16 applications are for cell culture, ELISA standard, and Western Blot Control. Cynomolgus Monkey IL-16 yeast-derived recombinant protein can be purchased in multiple sizes. Cynomolgus Monkey IL-16 Specifications: (Molecular Weight: 13.4 kDa) (Amino Acid Sequence: PDLNSTTDSA ASASAASDVS VESSAEATVY TVTLEKMSAG LGFSLEGGKG SLHGDKPLTI NRIFKGAASE QSETIQPGDE ILQLAGTAMQ GLTRFEAWNI IKALPDGPVT TVIRRKSLQP KETTAAADS (129) ) (Gene ID: 574100) . For research use only.

Product Specifications

Background

IL-16 is a pleiotropic cytokine that has been characterized as a chemoattractant for certain immune cells expressing the cell surface molecule CD4, and has effects on mixed lymphocyte reaction and inhibition of HIV viral replication. IL-16 forms homotetramers and this structure is required for its bioactivity. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. IL-16 is released by a variety of immune (T cells, esinophils, and dendritic cells) and non-immune (fibroblasts, epithelial, and neurona) cells. In the non-diseased state, IL-16 mRNA is almost exclusively expressed on lymphatic tissue, and high levels in T cells. During inflammation, IL-16 is synthesized in a number of other tissues.