Multi-species (Human, Monkey) Midkine Recombinant Protein

The Human & Monkey Midkine yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Human & Monkey Midkine applications are for cell culture, ELISA standard, and Western Blot Control. Human & Monkey Midkine yeast-derived recombinant protein can be purchased in multiple sizes. Human & Monkey Midkine Specifications: (Molecular Weight: 13.4 kDa) (Amino Acid Sequence: VAKKKDKVKK GGPGSECAEW AWGPCTPSSK DCGVGFREGT CGAQTQRIRC RVPCNWKKEF GADCKYKFEN WGACDGGTGT KVRQGTLKKA RYNAQCQETI RVTKPCTPKT KAKAKAKKGK GKD (123) ) (Gene ID:) . For research use only.

Product Specifications

Background

Midkine (MK or MDK) also known as neurite growth-promoting factor 2 (NEGF2) is a basic heparin-binding growth factor of low molecular weight, and forms a family with pleiotrophin. It is a developmentally important retinoic acid-responsive gene product strongly induced during mid-gestation, hence the name midkine. Restricted mainly to certain tissues in the normal adult, it is strongly induced during oncogenesis, inflammation and tissue repair. MK is pleiotropic, capable of exerting activities such as cell proliferation, cell migration, angiogenesis and fibrinolysis.

Sequence

VAKKKDKVKK GGPGSECAEW AWGPCTPSSK DCGVGFREGT CGAQTQRIRC RVPCNWKKEF GADCKYKFEN WGACDGGTGT KVRQGTLKKA RYNAQCQETI RVTKPCTPKT KAKAKAKKGK GKD (123)

Applications

Cell Culture, ELISA Standard, ELISpot Control, Western Blot Control

Homology

Chlorocebus sabaeus (green monkey), Gorilla gorilla gorilla (western lowland gorilla), Homo sapiens (human), Macaca mulatta (Rhesus monkey), Mandrillus leucophaeus (drill), Papio anubis (olive baboon), Pongo abelii (Sumatran orangutan), Rhinopithecus bieti (black snub-nosed monkey), Rhinopithecus roxellana (golden snub-nosed monkey), Theropithecus gelada (gelada)