Multi-species (Bovine, Caprine, Ovine, Rat, Swine) CXCL14 Recombinant Protein

CXCL14, also known as BRAK (breast and kidney-expressed chemokine) belongs to the CXC chemokine family. CXCL14 is constitutively expressed at high levels in many normal tissues, where its cellular source is thought to be fibroblasts. However, it is reduced or absent from most cancer cells. This chemokine is chemotactic for monocytes and can activate these cells in the presence of an inflammatory mediator called prostaglandin-E2 (PGE2) . It is also a potent chemoattractant and activator of dendritic cells, is implicated in homing of these cells, and can stimulate the migration of activated NK cells. CXCL14 also inhibits angiogenesis, possibly as a result of its ability to block endothelial cell chemotaxis.

Acomys russatus (golden spiny mouse), Apodemus sylvaticus (European woodmouse), Arvicanthis niloticus (Nile rat), Bison bison bison (American buffalo), Bos indicus (zebu), Bos mutus (wild yak), Bos taurus (cattle), Bubalus bubalis (water buffalo), Bubalus carabanensis (carabao), Budorcas taxicolor (takin), Capra hircus (goat), Cervus canadensis (elk), Chionomys nivalis (European snow vole), Echinops telfairi (small Madagascar hedgehog), Galeopterus variegatus (Sunda flying lemur), Hippopotamus amphibius kiboko (East African hippopotamus), Mastomys coucha (southern multimammate mouse), Meriones unguiculatus (Mongolian gerbil), Microtus fortis (reed vole), Microtus oregoni (creeping vole), Myodes glareolus (Bank vole), Nannospalax galili (Upper Galilee mountains blind mole rat), Odocoileus virginianus texanus (white-tailed deer), Onychomys torridus (southern grasshopper mouse), Ovis aries (sheep), Peromyscus eremicus (cactus mouse), Peromyscus leucopus (white-footed mouse), Peromyscus maniculatus bairdii (prairie deer mouse), Phacochoerus africanus (Common warthog), Phodopus roborovskii (desert hamster), Propithecus coquereli (Coquerel's sifaka), Psammomys obesus (fat sand rat), Rattus norvegicus (Norway rat), Rattus rattus (black rat), Sus scrofa (pig), Vicugna pacos (alpaca)