Ovine IL-22 ELISA

The Ovine IL-22 ELISA contains capture antibody, standard, and detection antibody for development of a Ovine IL-22 ELISA. The antibodies have been determined to function in an ELISA with the standard provided. Optimal buffers, concentrations, incubation times, incubation temperatures, and methods for the ELISA have not been determined. This allows for complete flexibility to provide optimal dynamic range and sensitivity based on your sample type. Alternate names include IL-22, IL-D110, IL-TIF, ILTIF, TIFIL-23, TIFa, zcyto18, interleukin 22. The quantities of components provided are not matched. Components may also be purchased separately. For research use only.

Product Specifications

Background

IL-22 is a member of the IL-10 family, which includes IL-19, IL-20, IL-24, and IL-26. This family represents a class of potent mediators of cellular inflammatory responses. IL-22 shares use of IL-10R2 in cell signaling with other members of this family. IL-22 is produced by activated DC and T cells and initiates innate immune responses against bacterial pathogens, especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 along with IL-17 is rapidly produced by a subset of splenic cells and can also be produced by Th17 cells. IL-22 likely plays a role in the coordinated response of both adaptive and innate immune systems.