Guinea Pig TNF alpha ELISA

The Guinea Pig TNF alpha ELISA contains capture antibody, standard, and detection antibody for development of a Guinea Pig TNF alpha ELISA. The antibodies have been determined to function in an ELISA with the standard provided. Optimal buffers, concentrations, incubation times, incubation temperatures, and methods for the ELISA have not been determined. This allows for complete flexibility to provide optimal dynamic range and sensitivity based on your sample type. Alternate names include TNF, DIF, TNF-alpha, TNFA, TNFSF2, Tumor necrosis factor, tumor necrosis factor, TNLG1F, Tumor necrosis factor alpha. The quantities of components provided are not matched. Components may also be purchased separately. For research use only.

Product Specifications

Background

TNF alpha is a member of the TNF Superfamily. It is produced chiefly by activated macrophages, but it is produced also by a broad variety of cell types including lymphoid cells, mast cells, endothelial cells, cardiac myocytes, adipose tissue, fibroblasts, and neuronal tissue. The primary role of TNF alpha is in the regulation of immune cells. TNF alpha, being an endogenous pyrogen, is able to induce fever, to induce apoptotic cell death, to induce sepsis (through IL-1 & IL-6 production), to induce cachexia, induce inflammation, and to inhibit tumorigenesis and viral replication.