Cynomolgus Monkey TIM-3 ELISA
The Cynomolgus Monkey TIM-3 ELISA contains capture antibody, standard, and detection antibody for development of a Cynomolgus Monkey TIM-3 ELISA. The antibodies have been determined to function in an ELISA with the standard provided. Optimal buffers, concentrations, incubation times, incubation temperatures, and methods for the ELISA have not been determined. This allows for complete flexibility to provide optimal dynamic range and sensitivity based on your sample type. The quantities of components provided are not matched. Components may also be purchased separately. For research use only.
Product Specifications
Background
TIM-3 is a transmembrane protein of T lymphocytes (CD4+ and CD8+ T cells), myeloid cells (monocytes, macrophages, DC, mast cells, NK cells) or various cells in different tumor types. The receptor is an immune checkpoint and together with other inhibitory receptors including programmed cell death protein 1 (PD-1) and lymphocyte activation gene 3 protein (LAG3) mediate the CD8+ T-cell exhaustion in terms of proliferation and secretion of cytokines such as TNF-alpha, IFN-gamma and IL-2.
Homology
Macaca fascicularis (crab-eating macaque)
Storage Temperature
2°C to 8°C or -20°C
Scientific Category
ELISA
Available Sizes
Curated Selection
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