Bovine IL-16 ELISA
The Bovine IL-16 ELISA contains capture antibody, standard, and detection antibody for development of a Bovine IL-16 ELISA. The antibodies have been determined to function in an ELISA with the standard provided. Optimal buffers, concentrations, incubation times, incubation temperatures, and methods for the ELISA have not been determined. This allows for complete flexibility to provide optimal dynamic range and sensitivity based on your sample type. The quantities of components provided are not matched. Components may also be purchased separately. For research use only.
Product Specifications
Background
IL-16 is a pleiotropic cytokine that has been characterized as a chemoattractant for certain immune cells expressing the cell surface molecule CD4, and has effects on mixed lymphocyte reaction and inhibition of HIV viral replication. IL-16 forms homotetramers and this structure is required for its bioactivity. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. IL-16 is released by a variety of immune (T cells, esinophils, and dendritic cells) and non-immune (fibroblasts, epithelial, and neurona) cells. In the non-diseased state, IL-16 mRNA is almost exclusively expressed on lymphatic tissue, and high levels in T cells. During inflammation, IL-16 is synthesized in a number of other tissues.
Homology
Bos indicus (zebu), Bos taurus (cattle)
Storage Temperature
2°C to 8°C or -20°C
Scientific Category
ELISA
Available Sizes
Frequently Asked Questions
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