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Multi-species (Bovine, Caprine, Ovine) IL-5 ELISA

The Bovine/Caprine/Ovine IL-5 ELISA contains capture antibody, standard, and detection antibody for development of a Bovine/Caprine/Ovine IL-5 ELISA. The antibodies have been determined to function in an ELISA with the standard provided. Optimal buffers, concentrations, incubation times, incubation temperatures, and methods for the ELISA have not been determined. This allows for complete flexibility to provide optimal dynamic range and sensitivity based on your sample type. The Bovine/Caprine/Ovine IL-5 ELISA can also be used to measure Bison and Zebu IL-5. The quantities of components provided are not matched. Components may also be purchased separately. For research use only.

Product Specifications

Background

IL-3, IL-5, and GM-CSF are important in regulating eosinophil development. Of these three cytokines, IL-5 is the most specific to the eosinophil lineage and is responsible for selective terminal differentiation of eosinophils. The IL-5 receptor is composed of an alpha and a beta-common chain. The alpha subunit is specific for the IL-5 molecule, whereas the beta-common subunit also recognized by IL-3 and GM-CSF. IL-5 is produced by both hematopoietic and non-hematopoietic cells including T cells, granulocytes, and natural helper cells. It is associated with the cause of several allergic diseases including allergic rhinitis and asthma.

Homology

Bison bison bison (American buffalo), Bos gaurus (gaur), Bos indicus (zebu), Bos taurus (cattle), Capra hircus (goat), Ovis aries (sheep)

Storage Temperature

2°C to 8°C or -20°C

Scientific Category

ELISA

Available Sizes

Frequently Asked Questions

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