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Canine Fas Ligand (TNFSF6) ELISA

The Canine Fas Ligand (FasL) ELISA contains capture antibody, standard, and detection antibody for development of a Canine Fas Ligand ELISA. The antibodies have been determined to function in an ELISA with the standard provided. Optimal buffers, concentrations, incubation times, incubation temperatures, and methods for the ELISA have not been determined. This allows for complete flexibility to provide optimal dynamic range and sensitivity based on your sample type. The Canine Fas Ligand ELISA can also be used to measure Dingo, and Red Fox Fas Ligand. Alternate names include FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6, TNLG1A, Fas ligand. The quantities of components provided are not matched. Components may also be purchased separately. For research use only.

Product Specifications

Background

Fas ligand, also known as CD95L and TNFSF6, is a homotrimeric type II transmembrane protein belonging to the tumor necrosis factor (TNF) superfamily. FasL plays diverse roles in the immune system, including induction of apoptotic cell death in target cells. FasL-Fas-mediated apoptosis plays fundamental roles in several immune functions. The pathway is involved in functions including regulation of T cell homeostasis and maintenance of immune privilege, apart from its well-established role in T cell-mediated cytotoxicity. Cytotoxicity via the Fas pathway is critical for prevention of pathogenic infections as well as control of tumor cell growth

Homology

Canis lupus dingo (dingo), Canis lupus familiaris (dog), Vulpes lagopus (Arctic fox), Vulpes vulpes (red fox)

Storage Temperature

2°C to 8°C or -20°C

Scientific Category

ELISA

Available Sizes

Frequently Asked Questions

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