Mouse CCL11 (Eotaxin-1) ELISA

The Mouse CCL11 (Eotaxin-1) ELISA contains capture antibody, standard, and detection antibody for development of a Mouse CCL11 ELISA. The antibodies have been determined to function in an ELISA with the standard provided. Optimal buffers, concentrations, incubation times, incubation temperatures, and methods for the ELISA have not been determined. This allows for complete flexibility to provide optimal dynamic range and sensitivity based on your sample type. Alternate names include CCL11, SCYA11, C-C motif chemokine ligand 11, Eotaxin-1, eosinophil chemotactic protein. The quantities of components provided are not matched. Components may also be purchased separately. For research use only.

Product Specifications

Background

CCL11 belongs to the CC chemokine family and is commonly known as Eotaxin-1. There are at least 27 distinct members of the C-C subgroup reported for mammals. CC chemokines induce the migration of monocytes and other cell types such as NK cells and dendritic cells. CCL11 selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. Endothelial cells, smooth muscle cells, epithelial cells, alveolar macrophages and eosinophils are known to produce CCL11.