Bovine CD86 Monoclonal Antibody (clone ILA190A)
CD86 (aka B7-2) is a protein found on activated B cells and monocytes. It provides a costimulatory signal necessary for T cell activation and survival. CD80 is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation) . CD80 works in tandem with CD86 to prime T cells. The Bovine CD86 monoclonal antibody, clone ILA159, has been qualified for use in flow cytometry, immunohistochemistry and cell function applications.
Product Specifications
Background
CD86 (aka B7-2) is a protein found on activated B cells and monocytes. It provides a costimulatory signal necessary for T cell activation and survival. CD80 is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation) . CD80 works in tandem with CD86 to prime T cells. The Bovine CD86 monoclonal antibody, clone ILA159, has been qualified for use in flow cytometry, immunohistochemistry and cell function applications.
Host
Mouse
Isotype
IgG1
Applications
Flow Cytometry
Purification
Produced in ascites fluid, clarified by filtration through a 0.2 micrometer filter.
Storage Temperature
2°C to 8°C
Scientific Category
Antibody
Curated Selection
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