Common Vampire Bat IL-22 Polyclonal Antibody - Biotinylated

The Common Vampire Bat IL-22 polyclonal antibody is labeled and has been qualified for use in ELISA. It is the detection antibody in the Kingfisher Common Vampire Bat IL-22 ELISA. The Common Vampire Bat IL-22 antibody was produced in rabbits and is antigen-affinity purified. The reactivity by species is: (Common vampire bat IL-22 - Strong) (Bovine IL-22 - None) (Caprine IL-22 - None) (Chicken IL-22 - None) (Cynomolgus monkey IL-22 - None) (Ferret IL-22 - None) (Mouse IL-22 - None) (Ovine IL-22 - None) (Rabbit IL-22 - None) (Swine IL-22 - None) . For research use only.

Product Specifications

Background

IL-22 is a member of the IL-10 family, which includes IL-19, IL-20, IL-24, and IL-26. This family represents a class of potent mediators of cellular inflammatory responses. IL-22 shares use of IL-10R2 in cell signaling with other members of this family. IL-22 is produced by activated DC and T cells and initiates innate immune responses against bacterial pathogens, especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 along with IL-17 is rapidly produced by a subset of splenic cells and can also be produced by Th17 cells. IL-22 likely plays a role in the coordinated response of both adaptive and innate immune systems.