Canine BAFF Polyclonal Antibody - Biotinylated

The Canine BAFF (TNFSF13B) polyclonal antibody is labeled and has been qualified for use in ELISA. It is the detection antibody in the Kingfisher Canine BAFF ELISA. The Canine BAFF antibody was produced in rabbits and is antigen-affinity purified. The reactivity by species is: (Bovine BAFF - None) (Canine BAFF - Strong) (Chicken BAFF - None) (Equine BAFF - None) (Feline BAFF - None) (Mouse BAFF - Moderate) (Ovine BAFF - None) (Rabbit BAFF - None) (Swine BAFF - None) .

Product Specifications

Background

BAFF (B-cell Activation Factor), also know as Tumor Necrosis Factor Superfamily member 13B is a member of the tumor necrosis factor ligand (TNF) ligand family. Nineteen cytokines have been identified as part of the TNF family on the basis of sequence, functional, and structural similarities. Family members include TNF beta (TNFSF1), TNF alpha, Lymphotoxin beta (TNFSF3), OX40 Ligand (TNFSF4), CD40 Ligand (TNFSF5), Fas Ligand (TNFSF6), CD27 Ligand (TNFSF7), CD30 Ligand (TNFSF8), 4-1BB Ligand (TNFSF9), TRAIL (TNFSF10), TRANCE/RANKL (TNFSF11), TWEAK (TNFSF12), APRIL (TNFSF13), BAFF, LIGHT (TNFSF14), TL1A/VEGI (TNFSF15), and GITR Ligand (TNFSF18) . BAFF is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells.