Bovine M-CSF Polyclonal Antibody

The Bovine M-CSF polyclonal antibody is unlabeled and has been qualified for use in ELISA and Western blot applications. It is the capture antibody in the Kingfisher Biotech Bovine M-CSF ELISA. The Bovine M-CSF antibody was produced in rabbits and is antigen-affinity purified. The reactivity by species is: (Bovine M-CSF - Strong) (Bat M-CSF - None) (Canine M-CSF - Weak) (Caprine M-CSF - Strong) (Chicken M-CSF - None) (Cynomolgus Monkey M-CSF - Weak) (Feline M-CSF - Weak) (Guinea Pig M-CSF - None) (Human M-CSF - Weak) (Mouse M-CSF - Weak) (Rabbit M-CSF - None) (Zebra finch M-CSF - None) . For research use only.

Product Specifications

Background

M-CSF (Macrophage colony-stimulating factor), also known as CSF-1, is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF enhances expression of differentiation antigens and stimulates chemotactic, phagocytic and the killing activities of monocytes. M-CSF also stimulates production of several cytokines, including GM- CSF, G-CSF and IL-6 by priming monocytes. It also stimulates production and secretion of IL-8 and reactive nitrogen intermediates. In addition to the stimulation of hematopoiesis, M-CSF also stimulates differentiation and proliferation of osteoclast progenitor cells and cytotrophoblasts.