Rabbit IL-17A Polyclonal Antibody

The Rabbit IL-17A polyclonal antibody is unlabeled and has been qualified for use in ELISA and Western blot applications. It is the capture antibody in the Kingfisher Biotech Rabbit IL-17A ELISA. The Rabbit IL-17A antibody was produced in chickens and is antigen-affinity purified. The reactivity by species is: (Bovine IL-17A - Strong) (Canine IL-17A - Strong) (Equine IL-17A - Strong) (Human IL-17A - Strong) (Mouse IL-17A - None) (Ovine IL-17A - Strong) (Rabbit IL-17A - Strong) (Rat IL-17A - Strong) (Swine IL-17A - Weak) . For research use only.

Product Specifications

Background

IL-17A is a member of the IL-17 family, which is comprised of 6 members [IL-17A, IL-17B, IL-17C, IL-17D, IL-17E (also called IL-25), and IL-17F]. IL-17 family members are involved in numerous immune regulatory functions, including inducing and mediating proinflammatory responses and allergic responses. IL-17 induces the production of many other cytokines (IL-6, G-CSF, GM-CSF, IL-1β, TGF-β, and TNF-α), chemokines, including IL-8, GRO-α (CXCL1) and MCP-1 (CCL2) and prostaglandins from many cell types (fibroblasts, endothelial cells, epithelial cells, keratinocytes and macrophages) .