Zebrafish IFN gamma 1-1 Polyclonal Antibody

The Zebrafish IFN gamma 1-1 polyclonal antibody is unlabeled and has been qualified for use in ELISA and Western blot applications. It is the capture antibody in the Kingfisher Biotech Zebrafish IFN gamma 1-1 ELISA. The Zebrafish IFN gamma 1-1 antibody was produced in rabbits and is antigen-affinity purified. The reactivity by species is: (Bovine IFN gamma - None) (Canine IFN gamma - None) (Caprine IFN gamma - None) (Chicken IFN gamma - None) (Cynomolgus Monkey IFN gamma - None) (Dolphin IFN gamma - None) (Equine IFN gamma - None) (Feline IFN gamma - None) (Human IFN gamma - None) (Mouse IFN gamma - None) (Ovine IFN gamma - None) (Rabbit IFN gamma - None) (Swine IFN gamma - None) (Zebrafish IFN gamma 1-1 - Strong) (Zebrafish IFN gamma 1-2 - None) . For research use only.

Product Specifications

Background

IFN gamma is a dimerized soluble cytokine that is the only member of the type II class of interferons. This interferon was originally called macrophage-activating factor, a term now used to describe a larger family of proteins to which IFN-γ belongs. IFN-γ is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFN-γ expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFN-γ in the immune system stems in part from its ability to inhibit viral replication directly, but, most important, derives from its immunostimulatory and immunomodulatory effects. IFN-γ is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.