Equine IL-12/IL-23 p40 Polyclonal Antibody - Biotinylated

The Equine IL-12 (IL-23) p40 polyclonal antibody is labeled and has been qualified for use in ELISA. It is the detection antibody in the Kingfisher Biotech Equine IL-12 (IL-23) p40 ELISA. The Equine IL-12 (IL-23) p40 antibody was produced in rabbits and is antigen-affinity purified. The reactivity by species is: (Bovine IL-12 p40 - Weak) (Chicken IL-12 p40 - Weak) (Equine IL-12 p40 - Strong) (Ovine IL-12 p40 - Moderate) (Swine IL-12 p40 - Moderate) . For research use only.

Product Specifications

Background

IL-12 is a member of the IL-12 family, which includes IL-12, IL-23, IL-27, and IL-35. Like other IL-12 family members, IL-12 is a heterodimeric cytokine. IL-12 is encoded by two separate genes, IL-12A (p35) and IL-12B (p40) . The active heterodimer, and a homodimer of p40 are formed following protein synthesis. IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of IFN-γ and TNF-α from T and natural killer (NK) cells, and reduces IL-4 mediated suppression of IFN-γ.