Swine IL-4 Polyclonal Antibody

The Swine IL-4 polyclonal antibody is unlabeled and has been qualified for use in ELISA and Western blot applications. It is the capture antibody in the Kingfisher Biotech Dolphin IL-4 ELISA. The Swine IL-4 polyclonal antibody was produced in goats and is antigen-affinity purified. The reactivity by species is: (Bovine IL-4 - Moderate) (Chicken IL-4 - None) (Dolphin IL-4 - Strong) (Equine IL-4 - None) (Feline IL-4 - Moderate) (Human IL-4 - None) (Mouse IL-4 - Weak) (Rabbit IL-4 - Weak) (Swine IL-4 - Strong) . For research use only.

Product Specifications

Background

IL-4 induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cells subsequently produce additional IL-4. IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. IL-4 induces B-cell class switching to IgE, and up-regulates MHC class II production. Overproduction of IL-4 is associated with allergies.