Canine IL-21 Polyclonal Antibody
The Canine IL-21 polyclonal antibody is unlabeled and has been qualified for use in ELISA and Western blot applications. It is the capture antibody in the Kingfisher Biotech Canine IL-21 ELISA. The Canine IL-21 polyclonal antibody was produced in rabbits and is antigen-affinity purified. The reactivity by species is: (Bovine IL-21 - None) (Canine IL-21 - Strong) (Chicken IL-21 - None) . For research use only.
Product Specifications
Background
IL-21 is a member of the type I cytokine family, which includes IL-2 and IL-15. IL-21 signals through the common gamma-chain and a unique IL-21 receptor. The IL-21 receptor is expressed in cells lymphoid-lineage and regulates the proliferation and differentiation of T and B lymphocytes. Studies suggest that IL-21 is a key component of CD4 T cell help that is required for maintaining the CD8+ T cell responses and inducing B cell antibody response. IL-21 also promotes the development of Th17 and Tfh cells, modulates the cytotoxic activity and survival of NK and CD8+ T cells, and suppresses the maturation of dendritic cells. It is also implicated in the development of autoimmune disease and has antitumor activity.
Host
Rabbit
Label
Unconjugated
Applications
ELISA, ELISpot, Flow Cytometry, Neutralization, Western Blot
Purification
Antigen-affinity
Homology
Canis lupus dingo (dingo), Canis lupus familiaris (dog), Nyctereutes procyonoides (raccoon dog)
Storage Temperature
2°C to 8°C
Scientific Category
Antibody
Available Sizes
Curated Selection
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