Bovine CD172a Monoclonal Antibody (clone DH59B) - Serum-free Media
CD172a, also known as Signal regulatory protein α (SIRPα), is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons. CD172a acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47. This interaction negatively controls effector function of innate immune cells such as host cell phagocytosis.
Product Specifications
Background
CD172a, also known as Signal regulatory protein α (SIRPα), is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons. CD172a acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47. This interaction negatively controls effector function of innate immune cells such as host cell phagocytosis.
Host
Mouse
Isotype
IgG1
Applications
Flow Cytometry
Purification
Produced in serum free medium with supplement. The stock was filtered through a 0.2 micrometer filter.
Storage Temperature
2°C to 8°C
Scientific Category
Antibody
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