Bovine CD172a Monoclonal Antibody (clone DH59B) - Serum-free Media

CD172a, also known as Signal regulatory protein α (SIRPα), is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons. CD172a acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47. This interaction negatively controls effector function of innate immune cells such as host cell phagocytosis.