Cynomolgus Monkey TNF alpha Polyclonal Antibody - Biotinylated

The Cynomolgus Monkey TNF alpha polyclonal antibody is labeled and has been qualified for use in ELISA applications. It is the detection antibody in the Kingfisher Biotech Cynomolgus Monkey TNF alpha ELISA. The Cynomolgus Monkey TNF alpha antibody was produced in rabbits and is antigen-affinity purified. The Cynomolgus Monkey TNF alpha polyclonal antibody has been shown to not cross-react with atlantic salmon, bovine, canine, caprine, dolphin, equine, feline, ferret, guinea pig, human, mouse, ovine, rabbit, swine and zebrafish TNF alpha. For research use only.

Product Specifications

Background

TNF alpha is a member of the TNF Superfamily. It is produced chiefly by activated macrophages, but it is produced also by a broad variety of cell types including lymphoid cells, mast cells, endothelial cells, cardiac myocytes, adipose tissue, fibroblasts, and neuronal tissue. The primary role of TNF alpha is in the regulation of immune cells. TNF alpha, being an endogenous pyrogen, is able to induce fever, to induce apoptotic cell death, to induce sepsis (through IL-1 & IL-6 production), to induce cachexia, induce inflammation, and to inhibit tumorigenesis and viral replication.