Equine IL-15 Polyclonal Antibody

The Equine IL-15 polyclonal antibody is unlabeled and has been qualified for use in ELISA and Western blot applications. It is the capture antibody in the Kingfisher Biotech Equine IL-15 ELISA. The Equine IL-15 polyclonal antibody was produced in goats and is antigen-affinity purified. The reactivity by species is: (Bovine IL-15 - Moderate) (Chicken IL-15 - None) (Equine IL-15 - Strong) (Guinea Pig IL-15 - Weak) (Swine IL-15 - Moderate) . For research use only.

Product Specifications

Background

IL-15 is a cytokine with structural similarity to IL-2 that is secreted by mononuclear phagocytes (and some other cells) following infection by virus (es) . This cytokine induces cell proliferation of natural killer cells; cells of the innate immune system whose principal role is to kill virally infected cells. IL-15 was discovered to be a member of a family of cytokines, which also includes IL-2, IL-4, IL-7, IL-9, and IL-21. The specific receptor for IL-15, IL-15 receptor alpha, appears to regulate IL-15 secretion, stability, and activity. All members of this family use the common gamma chain as part of their signaling complex. IL-15 has been shown to play a role in many diseases, including obesity, influenza, and inflammatory autoimmune diseases.