Mirabegron
Mirabegron is a selective β3-adrenoceptor agonist with EC50 of 22.4 nM.
Product Specifications
CAS Number
[223673-61-8]
Product Name Alternative
YM178
UNSPSC
12352005
Hazard Statement
H361
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Endocrinology; Cancer
Assay Protocol
https://www.medchemexpress.com/mirabegron.html
Purity
99.90
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=C(CCNC[C@H](O)C2=CC=CC=C2)C=C1)CC3=CSC(N)=N3
Molecular Formula
C21H24N4O2S
Molecular Weight
396.51
Precautions
H361
References & Citations
[1]Takasu T, et al. Effect of (R) -2- (2-aminothiazol-4-yl) -4'-{2-[ (2-hydroxy-2-phenylethyl) amino]ethyl} acetanilide (YM178), a novel selective beta3-adrenoceptor agonist, on bladder function. J Pharmacol Exp Ther. 2007 May;321 (2) :642-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β adrenergic receptor
Available Sizes
Curated Selection
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