Recombinant Sheep P-selectin (SELP)

CD62 antigen-like family member P; CD62P antigen; Granule membrane protein 140; Leukocyte-endothelial cell adhesion molecule 3; Platelet activation dependent granule-external membrane protein

LMTQKEVSAWTYHYSDKPYSWNYSRAFCQKYYTDLVAIQNKNEIAYLNETIPYYNSYYWIGIRKIDNKWTWVGTKKTLTEEAENWADNEPNNKKNNQDCVEIYIKSPSAPGKWNDEPCGKRKRALCYRASCQDMSCSKQGECIETIGNYTCSCYPGFYGPECEYVRECGEFDLPQNVHMNCSHPLGNFSFKSQCSFHCAEGYALNGPRELECLASGIWTNSPPQCVAVQCPALKSPEQGSMSCFHSAKAFQHQSSCSFSCEEGFTLVGPEVVHCTALGVWTAPTPVCKAIACESLESPVHGSMDCSPSPRAFQYNTSCSFRCAEGFTLRGADTVRCADSGEWTAPAPVCQALQCQDLPTSNKARVNCSHPFGDFRYQSTCSFTCDEGSFLVGASVLQCLDTGNWDAPFPECQAVTCAPLPNPQNGEKTCVQPLGGSSYKSTCWFTCHEGFSLSGPERLDCTPSGHWTGSPPTCEASKCPELSAPEQGSLDCPDTHGEFIVGSICHFSCNEGLKLEGSNHVECTASGRWTAPPPSCKVDTVSAPAPGLRCPSLIAPNQGTMSCQHHLRNFGLNTTCHFGCKAGFTLMGESALQCRPSRQWTAVAPTCRAVKCSKLPVTEPIVMNCSNPWGNFSYGSTCSFHCPEGQLLNGSERTACQENGQWSTTMPTCQAGPLTIQEALTYIGGAAAGTTGLVTSSILLALLRRRRRQKDDGKSPLNPQSHLGTYGVFTNAAFDPSP

Ca (2+) -dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG. Mediates cell-cell interactions and cell adhesion via the interaction with integrin alpha-IIb/beta3 (ITGA2B:ITGB3) and integrin alpha-V/beta-3 (ITGAV:ITGB3)

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.