PTH (7-34), Human

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Human Parathyroid Hormone (PHT) ParathyrinParathormoneParathyroid Hormone 1 (PTH1) Human Parathyroid Hormone (PTH) is a hormone expressed and secreted as preproPTH by chief cells of the parathyroid glands when extracellular calcium levels are low. It is coexpressed with furin, the enzyme believed to be responsible for processing proPTH to PTH. PTH is secreted as a midregional peptide fragment (7-34) when extracellular calcium levels are high, offsetting the effects of PTH. PTH plays a major role in bone metabolism and calcium homeostasis, as well as renal excretion. PTH (7-34) is a PTH1R antagonist capable of stimulating proliferation and differentiation of hair follicles and epidermis while promoting cell survival by activation of Akt.Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.Source:Escherichia coliMW: ~3.4 kDa (28 amino acids) Purity: >97% by SDS-PAGE and HPLC analysesBiological Activity: Fully biologically active when compared to standard. The specific activity is determined by UMR106 cell/cAMP method, corresponding to a specific activity of >1.0x104IU/mg.