PRL, Murine

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Murine Prolactin (PRL) Lactogenic HormoneLactotropinMammotropinLuteotropinMurine Prolactin (PRL) is a peptide hormone that is secreted most notably from the pituitary gland where it acts in an endocrine fashion, but also from extra pituitary regions where it acts in an autocrine or paracrine fashion. PRL serves as a ligand for the prolactin receptor, PRLR. It is listed as having over 300 separate functions and is involved in more processes than any other pituitary hormone. PRL is most commonly known for its lactation stimulating effect, but also plays a role in reproductive behavior, homeostasis of electrolytes, growth and development, regulation of metabolism, immune system regulation, angiogenesis, and survival of cancer cells. Homozygous female knock-out mice lacking expression of PRL become infertile, whereas homozygous males were fully fertile.Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.Source:Escherichia coliMW: ~22.4 kDa (197 amino acids) Purity: >98% by SDS-PAGE and HPLC analysesBiological Activity: Fully biologically active when compared to standard. The ED50as determined by a cell proliferation assay using rat Nb2-11 cells is less than 1.0 ng/ml, corresponding to a specific activity of >1.0x106IU/mg.