VEGF120, Murine

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Murine Vascular Endothelial Growth Factor120VEGF120Vascular Endothelial Growth Factor is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. VEGF is expressed in vascularized tissues and plays a prominent role in normal and pathological angiogenesis. VEGF has been implicated in the induction of tumor metastasis, intra-ocular neovascular syndromes and angiogenesis. Three mouse cDNA clones (monomeric VEGF having 120, 164 or 188 amino acids) have been identified through alternative splicing. Two receptor tyrosine kinases (RTKs), Flt-1 and Flk-1 (the mouse homologue of human KDR) have been shown to bind VEGF with high affinity.Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.Source:Escherichia coliMW: ~28.4 kDa (2x121 amino acid) (A disulfide linked homodimeric protein with two 165 amino acid polypeptide chains) Purity: >96% by SDS-PAGE and HPLC analyses