IFN-lambda2 (IL28A), Murine

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Murine Interferon Lambda 2IFNL2Interleukin 28A (IL28A) Interleukin-28-AlphaInterferon lambda 2, also known as interleukin 28A, belongs to the newly classified type III interferon family. Expression of IFNL2 is seen in a variety of cell types in response to viral infection or treatment with double-stranded RNA. IFNL2 exerts antiviral activity by activating mx proteins, 2',5'-oligoadenylate synthetase, and interferon regulatory factor 9. It signals through a heterodimeric receptor complex composed of IL10RB and IFNLR1 which activates the JAK-STAT pathway, phosphorylating STAT1, STAT2, and STAT3.Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.Source:Escherichia coliMW: ~19.7 kDa (174 amino acids) Purity: >95% by SDS-PAGE and HPLC analysesBiological Activity: Fully biologically active when compared to standard. The ED50as determined by an anti­viral assay using human HepG2 cells infected with encephalomyocarditis is less than 3 ng/ml, corresponding to a specific activity of >3.3x105IU/mg.