IL36RN (IL-36RA), Human

Goldbio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Human Interleukin-36RAIL36RA, IL36RNInterleukin 1 Receptor Antagonist Homolog 1 (IL1HY1) Interleukin 1 Family, Member 5 (IL1F5) Family of Interleukin 1-δ (FIL1-δ) Interleukin-36 receptor antagonist (IL36RN) is a secreted protein which belongs to the interleukin 1 cytokine family (IL1 family) and is predominantly expressed in keratinocytes but not in fibroblasts, endothelial cells or melanocytes. IL36RN has been reported to antagonize the biological activity of IL36A (IL1F6), IL36B (IL1F8), and IL36G (IL1F9) . Furthermore, it could constitute part of an independent signaling system analogous to IL1A, IL1B receptor agonist and interleukin-1 receptor type I (IL1R1) . However, the receptor for IL36RN has not been positively identified. Indirect evidence suggests that IL1Rrp2 is its receptor. Recombinant human IL36RN contains 154 amino acid residues and shares 91% amino acid sequence identity with murine IL36RN.Sterile Filtered White Lyophilized Powder. Purified and tested for use in cell culture.Source:Escherichia coliMW: ~16.8 kDa (154 amino acids) Purity: >95% by SDS-PAGE and HPLC analyses.Store desiccated at -20°C.NOT FOR HUMAN USE!HGNC:15561Cross-species homologyPercent SimilarityHuIL36RNMuIL36RNHuIL36RN***91%MuIL36RN******Additional resources for this protein may be found at:OMIM