IL36B (IL-36 beta), Human (157 a.a.)

Goldbio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Human Interleukin-36βIL36B, IL36βInterleukin 36βInterleukin 1 Family, Member 8 (IL1F8) Interleukin-36B (IL36B) is a pro-inflammatory cytokine that plays an important role in the pathophysiology of several diseases. IL36A, IL36B and IL36G (formerly IL1F6, IL1F8, and IL1F9) are IL1 family members that signal through the IL1 receptor family members IL1Rrp2 (IL1RL2) and IL1RAcP. IL36B has been reported to be expressed at higher levels in psoriatic plaques rather than symptomless psoriatic skin or healthy control skin. Furthermore, IL36B can stimulate production of IL6 and IL8 in synovial fibroblasts, articular chondrocytes and mature adipocytes. Human IL36B shares low sequence identity with IL1B, IL36RN, IL36A and IL36G.Sterile Filtered White Lyophilized Powder. Purified and tested for use in cell culture.Source:Escherichia coliMW: ~17.7 kDa (157 amino acids) Purity: >97% by SDS-PAGE and HPLC analyses.