IL36A (IL-36 alpha), Murine (160 a.a.)

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Murine Interleukin-36αIL36A, IL36αInterleukin 36αInterleukin 1 Family, Member 6 (IL1F6) Interleukin-36A (IL36A) is a pro-inflammatory cytokine, which plays an important role in the pathophysiology of several diseases. IL36A, IL36B, and IL36G (formerly IL1F6, IL1F8, and IL1F9) are all IL1 family members that signal through the IL1 receptor family members IL1Rrp2 (IL1RL2) and IL1RAcP. IL36A is mainly found in skin and lymphoid tissues, but can also be found in the fetal brain, trachea, stomach and intestine. IL36A is expressed by monocytes, B-cells and T-cells. Notably, IL36A is the only novel IL1 family member expressed on T-cells. Recombinant murine IL36A contains 160 amino acid residues which compose a single nonglycosylated polypeptide. Specifically, mouse IL36A shares 83% amino acid sequence identity with rat IL36A, 54-60% with human, rabbit, equine and bovine IL36A.Sterile Filtered White Lyophilized Powder. Purified and tested for use in cell culture.Source:Escherichia coliMW: ~18.0 kDa (160 amino acids) Purity: >95% by SDS-PAGE and HPLC analyses.