IL36A (IL-36 alpha), Human (158 a.a.)

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Human Interleukin-36αIL35A IL36αInterleukin 36αInterleukin 1 Family, Member 6 (IL1F6) Interleukin-36A (IL36A) is a pro-inflammatory cytokine that plays an important role in the pathophysiology of several diseases. IL36A, IL36B and IL36G (formerly IL1F6, IL1F8, and IL1F9) are IL1 family members that signal through the IL1 receptor family members IL1Rrp2 (IL1RL2) and IL1RAcP. Studies have shown that IL36A is mainly found in the skin and lymphoid tissues, as well as fetal brain, trachea, stomach and intestine. Notably, IL36A is the only novel IL1 family member expressed on T-cells. IL36A contains 158 amino acid residues which make up a single nonglycosylated polypeptide that is 30% homologous in amino acid sequence to IL1ra, and 27%, 31%, 36%, 46%, 57% and 28% homologous to IL1G, IL36Ra/IL1F5, IL37/IL1F7, IL36G/IL1F8, IL36H/IL1F9 and IL1F10 respectively.Sterile Filtered White Lyophilized Powder. Purified and tested for use in cell culture.Source:Escherichia coliMW: ~17.7 kDa (158 amino acids) Purity: >95% by SDS-PAGE and HPLC analyses.