FGF23, Human

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Human Fibroblast Growth Factor 23FGF-23FGF23 is a member of the Fibroblast Growth Factor family of proteins. In the FGF family, FGF23 is most closely associated with FGF15/19 and FGF21 (see additional information) . FGF23 shares 71% homology with mouse Fgf23 at the amino acid level. FGF23 is produced by osteocytes and osteoblasts in response to high circulating phosphate levels, elevated parathyroid hormone, and circulatory volume loading. It functions as an endocrine phosphatonin by suppressing circulating phosphate levels. FGF23 interaction with renal proximal tubular epithelium decreases the renal resorption of phosphate by down regulating phosphate transporters and by suppressing vitamin D production. It also decreases the intestinal absorption of phosphate.Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.Source:Escherichia coliMW: ~15.5 kDa (134 amino acid) Purity: >97% by SDS-PAGE and HPLC analyses