EGF, Human

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Human Epidermal Growth FactorEGFHMGF (Human Milk Growth Factor) PGF (Prostatic Growth Factor) EGF (Epidermal Growth Factor) is a family of growth factors that are derived from membrane-anchored precursors. The family is characterized by the presence of at least one “EGF-like domain” (characterized by the presence of three disulfide bonds, formed from 6 conserved cysteine residues) in their extracellular domain. EGF was originally discovered as an activity that induced early eyelid opening, incisor eruption, hair growth inhibition and stunting of growth when injected into newborn mice. Mature human EGF shares 70% amino acid sequence identity with mature mouse and rat EGF. Human EGF was isolated from urine based on its inhibitory effect on gastric secretion and is sometimes called urogastrone.Formulation: Sterile filtered white lyophilized powder. Purified and tested for use in cell culture.Sequence: NSDSECPLSH DGYCLHDGVC MYIEALDKYA CNCVVGYIGE RCQYRDLKWW ELRMW: ~6.2 kDa (53 amino acid) Purity: >98% by SDS-PAGE and HPLC analysesBiological activity: Fully biologically active when compared to standard. The ED50as determined by a cell proliferation assay using murine BALB/c 3T3 cells is less than 1 ng/ml, corresponding to a specific activity of >1.0x106IU/mg.Accession Number:P01133HGNC ID:3229Source:Escherichia coli