PPBP (CXCL7), Rat

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Rat Pro-Platelet Basic Protein (PPBP) Chemokine (C-X-C motif) Ligand 7 (CXCL7) Neutrophil-Activating Polypeptide 2 (NAP2, NAP-2) Small Inducible Cytokine Subfamily B Member 7 (SCYB7) Beta-Thomboglobulin (THBGB1) Rat PPBP is an ELR type of CXC chemokine. This recombinant protein is a mature, proteolytically processed form of PPBP that is also known as NAP2. It is expressed in monocytes and macrophages, especially from the lungs, after treatment with bacterial endotoxins and released from the alpha-granules of platelets after their activation. NAP2 is chemotactic for fibroblasts and neutrophils and binds to the receptor CXCR2. It is involved in a variety of cellular processes including mitogenesis, DNA synthesis, extracellular matrix synthesis, glycolysis, and plasminogen activator synthesis.Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.Source:Escherichia coliMW: ~6.8 kDa (62 amino acids) Purity: >97% by SDS-PAGE and HPLC analysesBiological Activity: Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human CXCR2 transfected murine BaF3 cells is in a concentration range of 0.1-1.0 ng/ml.