CXCL2, Rat

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Rat Chemokine (C-X-C motif) Ligand 2Melanoma Growth Stimulating Activity, Beta (MGSB, MGSA-b) Macrophage Inflammatory Protein 2 (MIP2, MIP2-alpha) Growth Related Oncogene 2 (GRO2, GRO-beta) Cytokine Induced Neutrophil Chemoattractant 2, Alpha (CINC2-alpha) Small Inducible Cytokine Subfamily B Member 2 (SCYB2) Rat CXCL2 is an ELR type of CXC chemokine. It is secreted by monocytes and macrophages and expressed in a variety of other cells. Expression of CXCL2 is induced by IL1, TNF, and LPS. CXCL2 participates in chemotaxis of neutrophils, basophils, polymorphonuclear leukocytes, and hematopoietic stem cells. It plays a role in would healing, angiogenesis, tumorigenesis, and pathogenesis of airway remodeling in asthma. CXCL2 exhibits antimicrobial activity against E. coli and S. aureus. CXCL2 is a ligand for CXCR2. CXCL2 shares significant amino acid sequence homology with CXCL1.Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.Source:Escherichia coliMW: ~7.9 kDa (73 amino acids) Purity: >98% by SDS-PAGE and HPLC analysesBiological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using rat neutrophils is in a concentration range of 10-100 ng/ml.