CXCL16, Murine

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Murine Chemokine (C-X-C motif) Ligand 16 (CXCL16) Scavenger Receptor For Phosphatidylserine And Oxidized Low Density Lipoprotein (SR-PSOX, SRPSOX) Small Inducible Cytokine Subfamily B Member 16 (SCYB16) Murine CXCL16 is a CXC chemokine lacking the ELR motif. It is expressed by macrophages, monocytes, B-cells, and Schwann cells. Expression is induced by IFNG and TNF-α. CXCL16 is an integral membrane protein that is cleaved by ADAM10 to release the soluble active polypeptide into the extracellular space. The soluble protein is chemotactic for activated CD8 T-cells, induces calcium flux and regulates migration of T-cells. CXCL16 is a ligand for CXCR6, but also serves as a receptor for oxidized LDL and phosphadtidylserine.Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.Source:Escherichia coliMW: ~9.9 kDa (88 amino acids) Purity: >98% by SDS-PAGE and HPLC analysesBiological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using murine lymphocytes is in a concentration range of 20-1000 ng/ml.