CXCL10, Rhesus macaque

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Rhesus Monkey Chemokine (C-X-C motif) Ligand 10 (CXCL10) Cytokine Responsive Gene 2 (CRG2) Small Inducible Cytokine Subfamily B Member 10 (SCYB10) Interferon Gamma Inducible Protein 10, (IP10, INP10) CXCL10 is a CXC chemokine lacking the ELR motif. It is expressed in and secreted by monocytes, endothelial cells, fibroblasts, and other cell types after induction by interferon gamma and may be an important mediator of inflammatory response to interferons. It is chemotactic for monocytes and T-cell lymphocytes. CXCL10 plays a role in angiostasis, inhibits bone marrow colony formation, and promotes T-cell adhesion to endothelial cells. CXCL10 also exhibits antimicrobial properties against Gram-positive and Gram-negative bacteria. It is closely related to CXCL9 and CXCL11, all three of which are ligands for CXCLR3.Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.Source:Escherichia coliMW: ~8.7 kDa (77 amino acids) Purity: >97% by SDS-PAGE and HPLC analysesBiological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood T-lymphocytes is in a concentration range of 10-50 ng/ml.