CX3CL1, Human

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Human Chemokine (C-X3-C motif) Ligand 1 (CX3CL1) FractalkineSmall Inducible Cytokine Subfamily D Member 1 (SCYD1) ATP-Binding Cassette, Subfamily D Member 3 (ABCD-3) Neurotactin (NTN) CX3CL1 is a chemokine that is unlike most chemokines because it contains the C-X-X-X-C motif. It is expressed by neurons, endothelial cells, follicular dendritic cells, and some lymphocytes. Expression of CX3CL1 is induced by activation of the transcription factor NFKB1 through IFNG, IL1B, TNF, or LPS. CX3CL1 is chemotactic for T-cells and monocytes and plays a role in angiogenesis, as well as regulation of leukocyte traffic at the endothelium. It also functions as a survival factor for microglial cells. CX3CL1 is a ligand for CX3CR1 as well as virus-encoded receptors M3 and US28.Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.Source:Escherichia coliMW: ~8.6 kDa (76 amino acids) Purity: >97% by SDS-PAGE and HPLC analysesBiological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 5-10 ng/ml.