CCL9 (CCL10), Murine

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Murine Chemokine (C-C motif) Ligand 9 (CCL9) Recombinant Murine Chemokine (C-C motif) Ligand 10 (CCL10) Small Inducible Cytokine Subfamily A Member 9 (SCYA9) Small Inducible Cytokine Subfamily A Member 10 (SCYA10) Macrophage Inflammatory Protein 1, Gamma (MIP1γ, MIP-1γ) MIP-related protein 2 (MRP2, MRP-2) CCF18CCL9 is a chemokine containing six conserved cysteine residues that form three disulfide bonds essential for biological activity. It circulates in the blood of healthy animals and is expressed constitutively in macrophages and myeloid cell lines. CCL9 displays chemotaxis for neutrophils, CD4+ T lymphocytes, and Peyer’s patch dendritic cells. Upon injection of CCL9, fever and inflammation are induced. CCL9 plays a major role in osteoclastogenesis and inhibits colony formation of bone marrow myeloid immature progenitors. It is a ligand for CCR1 and CCR3. Murine CCL9 has also been identified as murine CCL10 and is most homologous to Human CCL15.Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.Source:Escherichia coliMW: ~11.6 kDa (101 amino acids) Purity: >95% by SDS-PAGE and HPLC analysesBiological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration of 0.1-10 ng/ml.