CCL22, Human

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Human Chemokine (C-C motif) Ligand 22 (CCL22) Stimulated T Cell Chemotactic Protein 1 (STCP-1) Small Inducible Cytokine Subfamily A Member 22 (SCYA22) Macrophage-Derived Chemokine (MDC) CCL22 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed in thymus tissue, macrophages, and dendritic cells. Expression of CCL22 is induced by IL4 and IL13 and inhibited by IL10. It is chemotactic for chronically activated T cells and plays a role in trafficking activated T cells. It also plays a role in migration and survival of cells expressing FOXP3 in HTLV1 infection. CCL22 is a ligand for CCR4.Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.Source:Escherichia coliMW: ~8.1 kDa (69 amino acids) Purity: >97% by SDS-PAGE and HPLC analysesBiological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 10-100 ng/ml.