CCL21, Human

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Human Chemokine (C-C motif) Ligand 21 (CCL21) T Cell Activation 4 (TCA4, TCA-4) Small Inducible Cytokine Subfamily A Member 21 (SCYA21) Secondary Lymphoid Tissue Chemokine (SLC) Exodus 2CCL21 is a chemokine containing six conserved cysteine residues, two of which are adjacent. It is expressed in high endothelial venules of lymph nodes, as well as tonsils, breast stromal cells, and a variety of other cells. Expression of CCL21 is inhibited by IFNG. It is chemotactic for peripheral blood lymphocytes and plays a major role in initiation and expansion of adaptive immune responses, as well as development of local lymphoid tissue. CCL21 is a ligand for CCR7, as well as CXCR3 and the virorecptor M3.Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.Source:Escherichia coliMW: ~12.2 kDa (111 amino acids) Purity: >97% by SDS-PAGE and HPLC analysesBiological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human lymphocytes is in a concentration of 10-100 ng/ml.