CCL20, Murine

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Murine Chemokine (C-C motif) Ligand 20 (CCL20) Liver and Activation Regulated Chemokine (LARC) Small Inducible Cytokine Subfamily A Member 20 (SCYA20) Chemokine Beta 4 (Ckb4, Ck-β-4) Exodus, Exodus-1Macrophage Inflammatory Protein 3, Alpha (MIP3α, MIP-3α) CCL20 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed in the liver as well as in lymphocytes, monocytes, and leukemia cells that have been induced by a mediator of inflammation, such as IFNG, IL1B, LPS, or PMA. It is upregulated in psoriasis because of proinflammatory mediators produced in the skin and attracts T lymphocytes to lesions. CCL20 is chemotactic mainly for lymphocytes, but also for granulocytes and immature dendritic cells and it plays a role in development of mucosal lymphoid tissue. It is a ligand for CCR6.Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.Source:Escherichia coliMW: ~8.0 kDa (70 amino acids) Purity: >96% by SDS-PAGE and HPLC analysesBiological Activity: Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human CCR6 transfected murine BaF3 cells is in a concentration range of 0.1-10 ng/ml.