CCL18, Human

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Human Chemokine (C-C motif) Ligand 18 (CCL18) Pulmonary and Activation Regulated Chemokine (PARC) Small Inducible Cytokine Subfamily A Member 18 (SCYA18) Alternative Macrophage Activation-Associated CC Chemokine 1 (AMAC1, AMAC-1) Dendritic Cell Chemokine 1 (DCCK1, DC-CK1) Macrophage Inflammatory Protein 4 (MIP4, MIP-4) CCL18 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed constitutively in lung tissues and transiently in alveolar macrophages and follicular dendritic cells induced by IL4, IL10, IL13, LPS, or PMA. Expression of CCL18 is inhibited by IFNG. CCL18 is chemotactic for activated T-lymphocytes, non-activated lymphocytes, and basophils and likely plays a role in initiation of immune responses. It is a ligand for CCR8 and GPER1.Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.Source:Escherichia coliMW: ~7.9 kDa (69 amino acids) Purity: >97% by SDS-PAGE and HPLC analysesBiological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 1-10 ng/ml.