CCL1, Human

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!Recombinant Human Chemokine (C-C motif) Ligand 1 (CCL1) Inflammatory Cytokine I-309 (I309) Small Inducible Cytokine Subfamily A Member 1 (SCYA1) P500Small Inducible Secreted, Epsilon (SISE) T-Cell Activation (TCA-3) CCL1 is a chemokine containing four conserved cysteine residues, of which the first two are adjacent. It is expressed in and secreted from activated T-cells and it is chemotactic for monocytes, natural killer (NK) cells, and immature B-cells and dendritic cells. CCL1 has been shown to increase cytoplasmic calcium levels, protect T-cell lymphomas from apoptosis, and inhibit myeloid progenitors from proliferating. CCL1 is a ligand for CCR8 and is blocked by the viral CCR8 antagonist MC148R.Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.Source:Escherichia coliMW: ~8.6 kDa (74 amino acids) Purity: >97% by SDS-PAGE and HPLC analysesBiological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 10-100 ng/ml.