L-Homocysteine

Homocysteine is a cysteine homolog that differs by having an additional methylene bridge. It is often usedin vitroas a reference to measure L-homocysteine in plasma in order to diagnose homocystinuria. This genetic disorder causes the body to be unable to process certain amino acids.Homocysteine is biosynthesized from methionine through the intermediate S-adenosylmethionine. Homocysteine can then be converted to cysteine or back to methionine. The conversion to cysteine requires vitamin B6 as a cofactor while the conversion back to methionine requires vitamin B12. Increased levels of homocysteine in plasma can occur because of a vitamin B deficiency.Product SpecificationsL-HomocysteineMOLECULAR BIOLOGY GRADEFormula: C4H9NO2SMW: 135.19 g/molColor/Purity: White to off-white crystalline powder