Guanidine thiocyanate (Guanidine Isothiocyanate)

During cell lysis and the extraction of DNA or RNA, denaturing enzymes such as DNase and RNase are released. To prevent DNA or RNA denaturation, the chaotropic agent, Guanadine thiocyanate is the preferred agent for use during cell lysis, and for DNA or RNA extraction. This is because of its strong ability to irreversibly inhibit the activity of DNase and RNase.Guanadine thiocyanate has also been effective in deactivating enveloped viruses; however, it demonstrates far less effectiveness in nonenveloped viruses.Product SpecificationsGuanidine thiocyanateGuanidine IsothiocyanateFormula:CH5N3HSCNMW:118.16 g/molColor/Purity:White to slightly off-white crystalline powderForms a colorless, clear solution when dissolved 35% in water or forms a colorless, clear precipitate (carbonate) when dissolved 20% in acetone.PubChem Chemical ID:21226105