Caffeic acid phenethyl ester

Caffeic acid phenethyl ester (CAPE) is the active component of propolis, a honeybee hive product. Caffeic acid phenethyl ester is a specific inhibitor of the nuclear transcription factor, NF-κB. CAPE has been shown to significantly suppress the Lipoxygenase pathway of arachidonic acid metabolism during inflammation. Caffeic acid phenethyl ester inhibits HIV-1 integrase, and also inhibits proliferation of transformed cells. It induces apoptosis in transformed fibroblasts, and interferes with EGF signal transduction affecting both protein kinase C and Ornithine Decarboxylase activity.Product SpecificationsCaffeic acid phenethyl esterPhenethyl 3,4-Dihydroxycinnamate; CAPEMOLECULAR BIOLOGY GRADEFormula: C17H16O4MW: 284.310 g/molSlightly off-white to yellowish crystalline powder